Izumi Fukuda Selected Research

Insulin-Like Growth Factor II (Somatomedin A)

3/2022	Insulin-like growth factor II-producing colonic carcinoma presenting with non-islet cell tumor hypoglycemia: An autopsy report revealing neuroendocrine differentiation in the metastatic foci and literature review.
5/2021	Early Improvement of Non-islet Cell Tumor Hypoglycemia by Chemotherapy Using Lenvatinib in a Case with Type 2 Diabetes and Hepatocellular Carcinoma Producing Big IGF-II.
1/2021	Diagnostic potential of miR-483 family for IGF-II producing non-islet cell tumor hypoglycemia.
1/2021	Erratum for Early Improvement of Non-islet Cell Tumor Hypoglycemia by Chemotherapy Using Lenvatinib in a Case with Type 2 Diabetes and Hepatocellular Carcinoma Producing Big IGF-II.
7/2017	Levels of glucose-regulatory hormones in patients with non-islet cell tumor hypoglycemia: including a review of the literature.
7/2016	Late recurrence of a malignant hypoglycemia-inducing pelvic solitary fibrous tumor secreting high-molecular-weight insulin-like growth factor-II: A case report with protein analysis.
7/2015	Hypoglycemia Observed on Continuous Glucose Monitoring Associated With IGF-2-Producing Solitary Fibrous Tumor.
1/2015	Non-Islet Cell Tumor Hypoglycemia Is Caused by Big IGF-II in a Patient with a Carcinosarcoma of the Uterus.
9/2012	IGF-II Producing Hepatocellular Carcinoma Treated with Sorafenib: Metabolic Complications and a Foresight to Molecular Targeting Therapy to the IGF Signal.
1/2012	Recurrent solitary fibrous tumor of the pleura with malignant transformation and non-islet cell tumor-induced hypoglycemia due to paraneoplastic overexpression and secretion of high-molecular-weight insulin-like growth factor II.

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Izumi Fukuda Research Topics

Disease

18	Hypoglycemia (Reactive Hypoglycemia) 03/2022 - 09/2004
13	Islet Cell Adenoma (Islet Cell Tumors) 03/2022 - 08/2006
12	Neoplasms (Cancer) 03/2022 - 08/2006
5	Type 2 Diabetes Mellitus (MODY) 05/2021 - 07/2018
4	Hepatocellular Carcinoma (Hepatoma) 05/2021 - 08/2006
4	Insulin Resistance 11/2020 - 12/2004
4	Acromegaly 02/2014 - 06/2002
3	Carcinoma (Carcinomatosis) 03/2022 - 08/2006
3	Body Weight (Weight, Body) 01/2021 - 01/2014
2	Adrenocorticotropic hormone deficiency 08/2022 - 05/2021
2	Neoplasm Metastasis (Metastasis) 03/2022 - 07/2015
2	Hypothyroidism 05/2021 - 01/2009
2	Non-alcoholic Fatty Liver Disease 01/2021 - 01/2021
2	Liver Cirrhosis (Hepatic Cirrhosis) 01/2021 - 01/2021
2	Fibrosis (Cirrhosis) 01/2021 - 01/2021
2	Adenoma (Adenomas) 11/2020 - 01/2017
2	Hyperaldosteronism (Conn Syndrome) 11/2020 - 01/2017
2	Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor) 05/2020 - 01/2016
2	Solitary Fibrous Tumors 07/2016 - 07/2015
2	Stomach Neoplasms (Stomach Cancer) 08/2010 - 09/2004
1	Adenocarcinoma 03/2022
1	Colorectal Neoplasms (Colorectal Cancer) 03/2022
1	Sigmoid Neoplasms 03/2022
1	Fatty Liver 01/2021
1	Inflammation (Inflammations) 01/2021
1	Cardiac Sudden Death (Sudden Cardiac Arrest) 01/2021
1	Glucose Intolerance 11/2020
1	Paraneoplastic Syndromes (Paraneoplastic Syndrome) 05/2020
1	Pituitary Neoplasms (Pituitary Adenoma) 02/2020
1	Hypopituitarism (Sheehan's Syndrome) 02/2020
1	Diabetic Neuropathies (Diabetic Neuropathy) 07/2018
1	Sarcoma (Soft Tissue Sarcoma) 01/2015
1	Carcinosarcoma 01/2015
1	Sepsis (Septicemia) 01/2015
1	Adrenal Insufficiency (Adrenal Gland Hypofunction) 09/2012
1	Pleural Solitary Fibrous Tumor 01/2012
1	Sarcoidosis (Schaumann Disease) 01/2010
1	Graves Disease (Basedow Disease) 01/2009
1	Thyroid Diseases (Thyroid Disease) 01/2009
1	Thyroiditis 01/2009
1	Hypertriglyceridemia 08/2006
1	Malnutrition (Nutritional Deficiencies) 08/2006
1	Lipid Metabolism Disorders (Metabolism Disorders, Lipid) 08/2006
1	Hypercholesterolemia 08/2006
1	Atherosclerosis 12/2004
1	Coma (Comas) 09/2004
1	Neurogenic Diabetes Insipidus (Central Diabetes Insipidus) 08/2003

Drug/Important Bio-Agent (IBA)

13	Insulin-Like Growth Factor II (Somatomedin A)IBA 03/2022 - 09/2004
9	Insulin (Novolin)FDA Link 01/2021 - 01/2010
7	Glucose (Dextrose)FDA LinkGeneric 11/2020 - 08/2006
7	Insulin-Like Growth Factor I (IGF-1)IBA 07/2015 - 06/2002
6	Insulin-Like PeptidesIBA 03/2022 - 06/2002
5	Hypoglycemic Agents (Hypoglycemics)IBA 07/2016 - 09/2004
3	Growth Hormone (Somatotropin)IBA 05/2021 - 12/2004
3	Proteins (Proteins, Gene)FDA Link 01/2021 - 08/2006
2	Hormones (Hormone)IBA 05/2021 - 07/2017
2	lenvatinibIBA 05/2021 - 01/2021
2	Blood Glucose (Blood Sugar)IBA 01/2021 - 01/2021
2	AldosteroneIBA 11/2020 - 01/2017
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 05/2020 - 01/2016
2	SteroidsIBA 01/2010 - 09/2004
1	HLA Antigens (Human Leukocyte Antigens)IBA 08/2022
1	GonadotropinsIBA 05/2021
1	Pituitary HormonesIBA 05/2021
1	Prednisolone (Predate)FDA LinkGeneric 05/2021
1	Dipeptidyl-Peptidase IV InhibitorsIBA 05/2021
1	Hyaluronic Acid (Hyaluronan)IBA 01/2021
1	Uric Acid (Urate)IBA 01/2021
1	wisteria lectinIBA 01/2021
1	Sodium-Glucose Transport ProteinsIBA 01/2021
1	Alanine Transaminase (SGPT)IBA 01/2021
1	Heparin (Liquaemin)FDA LinkGeneric 09/2020
1	Insulin ReceptorIBA 05/2020
1	C-PeptideIBA 05/2020
1	growth hormone-releasing peptide-2 (KP 102)IBA 02/2020
1	AlbuminsIBA 07/2018
1	Adrenocorticotropic Hormone (ACTH)FDA Link 01/2017
1	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2017
1	GlucocorticoidsIBA 01/2016
1	Biomarkers (Surrogate Marker)IBA 07/2015
1	Sorafenib (BAY 43-9006)FDA Link 09/2012
1	Phosphotransferases (Kinase)IBA 09/2012
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 09/2012
1	Tyrosine (L-Tyrosine)FDA Link 09/2012
1	Messenger RNA (mRNA)IBA 01/2010
1	AutoantibodiesIBA 01/2009
1	Thyroid HormonesIBA 01/2009
1	Thyroxine (Levothyroxine)FDA LinkGeneric 01/2009
1	LDL CholesterolIBA 08/2006
1	HDL CholesterolIBA 08/2006
1	AdiponectinIBA 12/2004
1	PotassiumIBA 09/2004
1	Deamino Arginine Vasopressin (Desmopressin)FDA LinkGeneric 08/2003

Therapy/Procedure

10	Therapeutics 01/2021 - 08/2003
4	Glycemic Control 01/2021 - 07/2018
3	Drug Therapy (Chemotherapy) 05/2021 - 08/2018
1	Injections 01/2021
1	Intravenous Infusions 05/2020
1	Splenectomy 01/2010
1	Gastrectomy 09/2004